Regulus Therapeutics Inc (NASDAQ: RGLS) has initiated studies to evaluate a library of oligonucleotides to block miR-155 for Amyotrophic Lateral Sclerosis (ALS or Lou Gehrig's disease) under a collaboration agreement with Harvard's Brigham and Women's Hospital (BWH).
The agreement, effective since September 2021, encompasses the investigation of the biologic effects of miR-155 inhibitors in both in vitro and in vivo models of ALS.
Results from these initial studies will guide future experiments' design in additional animal models of the disease and characterize their properties.
Preliminary data from the studies are expected in 2H of 2022.
In animal models of ALS, miR-155 was found upregulated in microglia and associated with disease progression. Notably, miR-155 was also elevated in the spinal cord of patients with ALS.
Anti-miR-155 treatment suppressed disease-associated cytotoxic microglia, and resulted in robust improvement in clinically relevant disease endpoints, including prolongation of survival.
Price Action: RGLS shares are up 1.08% at $0.29 during the market session on the last check Thursday.
SPI Energy Co., Ltd. (NASDAQ: SPI) rose 36.3% to $3.87 in pre-market trading after reporting record revenue of $162 million for 2021.
Twitter, Inc. (NYSE: TWTR) rose 25.7% to $49.44 in pre-market trading after Elon Musk disclosed a 9.2% passive stake in the company.
Iron Spark I Inc. (NASDAQ: ISAA) rose 18% to $11.80 in pre-market trading. Hypebeast will list shares in U.S. through merger with Iron Spark I, the Wall Street Journal reported.
Context Therapeutics Inc. (NASDAQ: CNTX) shares rose 17.9% to $2.83 in pre-market trading after jumping over 10% on Friday. Context Therapeutics recently posted FY21 net loss of $10.5 million.
Borqs Technologies, Inc. (NASDAQ: BRQS) rose 15.9% to $0.2434 in pre-market trading. TDR Capital reported a new stake of 9.9% in Borqs Technologies.
Yumanity Therapeutics, Inc. (NASDAQ: YMTX) rose 13.1% to $1.73 in pre-market trading. Yumanity Therapeutics recently posted a FY21 loss of $3.84 per share.
Infobird Co., Ltd (NASDAQ: IFBD) shares rose 12.7% to $0.7899 in pre-market trading. Infobird recently announced receipt of delinquency notification letter from Nasdaq.
TMC the metals company Inc. (NASDAQ: TMC) rose 11.4% to $2.73 in pre-market trading.
Bilibili Inc. (NASDAQ: BILI) rose 10.8% to $30.60 in pre-market trading after surging 8% on Friday.
17 Education & Technology Group Inc. (NASDAQ: YQ) rose 10.6% to $3.02 in pre-market trading.
Enservco Corporation (NYSE: ENSV) rose 10% to $2.74 in pre-market trading after declining around 8% on Friday.
Lizhi Inc. (NASDAQ: LIZI) rose 9.6% to $1.60.
Expion360 Inc. (NASDAQ: XPON) rose 9% to $8.64 in pre-market trading. The company recently priced its IPO at $7 per share.
Siyata Mobile Inc. (NASDAQ: SYTA) rose 8.5% to $1.27 in pre-market trading after declining 6% on Friday.
Reed's, Inc. (NASDAQ: REED) rose 7.4% to $0.27 in pre-market trading after dipping 16% on Friday. Reed's recently reported worse-than-expected Q4 EPS and sales results.
Don’t forget to check out our premarket coverage here .
Losers
Iveda Solutions, Inc. (NASDAQ: IVDA) shares fell 13.7% to $3.25 in pre-market trading after climbing around 12% on Friday.
Liquid Media Group Ltd. (NASDAQ: YVR) shares fell 12.2% to $0.70 in pre-market trading after jumping 12% on Friday.
Weidai Ltd. (NYSE: WEI) fell 11.9% to $1.26 in pre-market trading after jumping 29% on Friday.
Curis, Inc. (NASDAQ: CRIS) fell 9.5% to $2.20 in pre-market trading.
ThermoGenesis Holdings, Inc. (NASDAQ: THMO) shares fell 9.4% to $0.6067 in pre-market trading. ThermoGenesis recently said FY21 sales results were down from last year.
Reed's, Inc. (NYSE: REED) fell 9.2% to $0.2730 in pre-market trading as the company reported fourth-quarter revenue growth of 20% year-over-year to $12.8 million, missing the consensus of $13.02 million.
Blackboxstocks Inc. (NASDAQ: BLBX) fell 9.1% to $2.91 in pre-market trading. Blackboxstocks shares surged 19% on Friday after the company reported better-than-expected Q4 sales results.
QualTek Services Inc. (NASDAQ: QTEK) fell 7.8% to $2.58 in pre-market trading. QualTek Services posted FY21 net loss from continuing operations of $49.1 million.
Hudson Capital Inc. (NASDAQ: HUSN) shares fell 7.2% to $2.44 in pre-market trading. Hudson Capital shares jumped 36% on Friday after the company announced it sold its wholly-owned subsidiary, Hong Kong Internet Financial Services, to private investors.
Ocugen, Inc. (NASDAQ: OCGN) fell 7% to $3.07 in pre-market trading.
ARCA biopharma, Inc. (NASDAQ: ABIO) fell 6.8% to $2.05 in pre-market trading. ARCA Biopharma recently reported the results from its Phase 2 trial of ASPEN-COVID did not meet the primary endpoint.
Roblox’s long-term growth relies on its ability to gain older users.
It’s also ramping up its international expansion.
A growing number of brands are joining its metaverse platform.
Roblox Corporation (NYSE:RBLX) posted stellar earnings on Feb. 15 for its fourth quarter and 2021 at large. As a result, RBLX stock could be worth significantly more than Friday’s numbers based on its powerful free cash flow (FCF).
Source: Katya Rekina/ Shutterstock.com
That is good news for holders of the stock, as it has had a rough time lately. Roblox is down significantly from its peak price of $134.72 on Nov. 19.
As of Friday, March 11, RBLX stock had fallen to $39.24, representing a drop of almost 71% from the peak. Moreover, from the end of last year, the stock is off 62% from $103.16, as of Dec. 31, 2021.
The Roblox stock price correction has gone too far. This is especially the case since the company is profitable. It also produces significant amounts of FCF which is key to its higher valuation.
This article was automatically generated by MarketWatch using technology from Automated Insights.
Shares of TherapeuticsMD Inc. (TXMD) slumped 0.69% to $0.37 Monday, on what proved to be an all-around positive trading session for the stock market, with the NASDAQ Composite Index rising 1.90% to 14,532.55 and the Dow Jones Industrial Average rising 0.30% to 34,921.88. This was the stock's fourth consecutive day of losses. TherapeuticsMD Inc. closed $1.10 below its 52-week high ($1.47), which the company achieved on April 9th.
The stock demonstrated a mixed performance when compared to some of its competitors Monday, as Johnson & Johnson (JNJ) fell 0.97% to $176.47, Merck & Co. Inc. (MRK) fell 0.04% to $83.49, and Novartis AG ADR (NOVN.EB) fell 0.41% to $87.33. Trading volume (2.5 M) remained 4.7 million below its 50-day average volume of 7.2 M.
Data source: Dow Jones Market Data, FactSet. Data compiled April 4, 2022.
AVCT Announces Intent to Effect Reverse Stock Split
6:54 pm ET September 29, 2022(Globe Newswire)Print
Common Stock Will Begin Trading on a Split-Adjusted Basis on October 3, 2022GlobeNewswireSeptember 29, 2022
ATLANTA, Sept. 29, 2022 (GLOBE NEWSWIRE) -- American Virtual Cloud Technologies, Inc.
(Nasdaq: AVCT) (the "Company") today announces that it intends to
effect a 1-for-15 reverse stock split of its issued and outstanding
shares of common stock (the "Reverse Stock Split"). The Reverse Stock
Split will become effective on September 30, 2022 (the "Effective Time")
upon filing with the Delaware Secretary of State of an amendment to the
Company's amended and restated certificate of incorporation (the
"Charter"), and the Company's common stock is expected to begin trading
on a split-adjusted basis when the market opens on October 3, 2022. The
Company's common stock will continue to trade on the Nasdaq Capital
Market under the symbol "AVCT." The new CUSIP number for the common
stock following the Reverse Stock Split will be 030382204.
As
previously disclosed, at the Company's annual meeting of stockholders
held on May 24, 2022, the Company's stockholders voted to approve three
alternative amendments to the Company's Charter to effect a Reverse
Stock Split of the Company's common stock at a ratio of either 1-for-5,
1-for-10 or 1-for-15, with such ratio and the implementation and timing
of such Reverse Stock Split to be determined by the Company's board of
directors. The board of directors subsequently approved the
implementation of a 1-for-15 Reverse Stock Split.
As a result of
the Reverse Stock Split, each share of common stock issued and
outstanding immediately prior to the Effective Time will be
automatically reclassified as and converted into one-fifteenth (1/15) of
a share of common stock. The Reverse Stock Split will affect all
stockholders uniformly and will not alter any stockholder's percentage
interest in the Company's equity, except to the extent that the Reverse
Stock Split would result in a stockholder owning a fractional share. No
fractional shares will be issued in connection with the Reverse Stock
Split. Stockholders who otherwise would be entitled to receive a
fractional share will instead be entitled to receive cash in lieu of
such fractional share from the Company's transfer agent, Continental
Stock Transfer and Trust Company.
The Reverse
Stock Split did not change the par value of the common stock or the
authorized number of shares of common stock. All outstanding warrants
and preferred stock entitling their holders to purchase or obtain or
convert into shares of our common stock will be adjusted, as required by
the terms of these securities.
About American Virtual Cloud Technologies, Inc.
American
Virtual Cloud Technologies ("AVCtechnologies"; Nasdaq: AVCT) now
operates under the Kandy brand name. Kandy establishes and operates
cloud-based communications marketplaces for telecom carriers, offering
proprietary API Enablement services such as Microsoft Teams Direct
Routing as a Service, and SIP Trunking as a Service capabilities. For
more information, visit https://www.avctechnologies.com.
This
press release includes certain statements that are not historical facts
but are forward-looking statements for purposes of the safe harbor
provisions under the United States Private Securities Litigation Reform
Act of 1995. Forward-looking statements generally are accompanied by
words such as "believe," "may," "will," "estimate," "continue,"
"anticipate," "intend," "expect," "should," "would," "plan," "predict,"
"potential," "seem," "seek," "future," "outlook," and similar
expressions that predict or indicate future events or trends or that are
not statements of historical matters. These forward-looking statements
include, but are not limited to, statements regarding the Reverse Stock
Split and other future events and expectations described in this press
release. The Company's actual results or outcomes and the timing of
certain events may differ significantly from those discussed in any
forward-looking statements. These statements are based on various
assumptions and on the current expectations of the Company's management
and are not predictions of actual performance. These forward-looking
statements are provided for illustrative purposes only and are not
intended to serve as, and must not be relied on by any investor as, a
guarantee, an assurance, a prediction or a definitive statement of fact
or probability.
Actual events and circumstances are difficult or
impossible to predict and will differ from assumptions. Many actual
events and circumstances are beyond the control of the Company. These
forward-looking statements are subject to a number of risks and
uncertainties, including the Company's need for additional funding to
continue as a going concern; the possibility that Nasdaq may delist the
Company's securities; changes in the Company's clients' preferences,
prospects and the competitive conditions prevailing in the industries in
which the Company operates; the Company's substantial indebtedness;
risks associated with the potential effects of COVID-19 on the Company's
business; risks that the recently-acquired Kandy Communications
business will not be integrated successfully; ability to retain key
personnel; and those factors discussed in the Company's annual report on
Form 10-K filed with the SEC on April 15, 2022 and quarterly report on
Form 10-Q filed with the SEC on August 16, 2022, in each case under the
heading "Risk Factors," and other documents of the Company filed, or to
be filed, with the SEC. If the risks materialize or assumptions prove
incorrect, actual results could differ materially from the results
implied by these forward-looking statements. There may be additional
risks that the Company presently does not know or that the Company
currently believes are immaterial that could also cause actual results
to differ from those contained in the forward-looking statements. In
addition, forward-looking statements reflect the Company's expectations,
plans or forecasts of future events and views as of the date of this
document. The Company anticipates that subsequent events and
developments will cause its assessments to change. However, while the
Company may elect to update these forward-looking statements at some
point in the future, the Company specifically disclaims any obligation
to do so. These forward-looking statements should not be relied upon as
representing the Company's assessments as of any date subsequent to the
date of this document. Accordingly, undue reliance should not be placed
upon the forward-looking statements.
